The objectives of the study are to
1. Determine the age-specific cumulative incidence of COVID-19 infection, as determined by seroconversion, among 1 to 4 years old children and mothers (women of reproductive age) enrolled in the AMANHI-ACT study.
2. Determine proportion of infections causing moderate or severe COVID-19 disease among women of reproductive age and children under-5 years of age.
3. Investigate epidemiological, biological, serological, socio-economic and nutritional status as possible risk factors for infection, and severity of disease given infection.
4. Evaluate the impact of asymptomatic or symptomatic SARS-CoV-2 infection on the risk of subsequent infection and severity of disease.
5. For pregnant women identified in the cohort:
a) Evaluate the clinical presentation, utilization of preventive care, complications, treatment and clinical course of disease for pregnant women or women who have delivered in the last eight weeks who are infected with COVID-19
b) Evaluate the pregnancy, delivery and newborn outcomes among those born to women who have had COVID-19 and identify subgroups that are at a higher for adverse outcomes.
c) To collect data in a harmonized manner and contribute to pooled analysis with other ongoing pregnancy in COVID-cohorts such as those conducted by WHO/SRH and PRIORITY network.
6. Document the non-COVID-19 related health care utilization for preventive and curative health services for pregnant and non-pregnant women and children and how these are affected by the COVID-19 epidemic.
Project Location: Pemba, Zanzibar, TZ
Project Started: Oct 2020
Funded By: World Health Organization (WHO
1. How to improve screening and identification of infants less than 6 months of age with growth failure;